The phenomenal proliferation of scientific studies into the nature of induced pluripotent stem (iPS) cells following publication of the findings of Takahashi and Yamanaka little more than 2 years ago, have significantly expanded our understanding of cellular mechanisms relating to cell lineage, differentiation, and proliferation. While the full potential of iPS cell lineages for both scientific tool and therapeutic applications is as yet unclear, findings from several lines of investigation suggests that multipotential and terminally differentiated cells from an array of (...) cell types are competent to undergo epigenetic reprogramming to a pluripotential state. The nature of this pluripotential state appears to be similar to, but not identical with that previously described for embryonic stem (ES) cells. Understanding the nature of this induced reprogrammed state will be critical to determining the full potential of iPS cells. Recently, this issue has been examined through an integrated analysis of the genome in fully and partially reprogrammed iPS cell lineages. These results provide a window onto the temporal components of reprogramming and suggest mechanisms by which the efficacy of reprogramming can be enhanced. (shrink)

This essay examines three works by three women writers whose strategies for rewriting the past include a revisionary engagement with the cultural legacies of Ancient Greece and Rome: The Emperor’s Babe: A Novel, Looking for Livingstone: An Odyssey of Silence, and Voyage of the Sable Venus. It argues that each embodies a mode of resistance that both protests the historic oppression of women of colour and asserts a black female agency, insisting on an empowered present and future. In achieving this, (...) all three transgress or subvert conventional generic distinctions between verse and prose, and, in Lewis’s case, between the cultural forms and academic disciplines of art, art history and literature. Each work insists on a transnational conception of black identity, implicitly tracing black diasporic experience through Africa, Europe and the Americas, and asserting the continued interconnections between these three. And, in their confrontations with the histories of colonialism, empire and slavery, each invokes not just the history of the seventeenth to twenty-first centuries ce but also the cultures of Ancient Greece and Rome, the legacies of which underpinned these modern European processes of domination. Of the three works discussed here, those by Evaristo and Lewis ultimately constitute works of greater subversive power than does that of Philip. (shrink)

Žižek’s objective violence presents a radical contribution to understanding how violence occurs, and broadening our understandings of what can be theorized as violence. However, a full account of objective violence spans across multiple texts, and at times lacks full detail. This article addresses this problem by first giving an account for objective violence based on a variety of Žižek’s works, and then analyzing how other theorists outside philosophy have used this theoretical tool in their own research contexts. Through this method, (...) the conclusion is drawn that the lack of detail in Žižek’s work has created the capacity for a collaborative philosophical project whereby theorists have been able to appropriate key features of this tool in order to make it relevant to a variety of research contexts. (shrink)

Recognizing gaps in our present understanding of leader apologies, this investigation examines how followers appraise leader apologies and how these perceptions impact work-related outcomes. Results indicate that followers who viewed their leader as trustworthy or caring before a leader wrongdoing were more likely to perceive their leader’s apology to be sincere, as compared to followers who previously doubted their leader’s trustworthiness and caring. Attributions of apology sincerity affected follower reactions, with followers perceiving sincere apologies reporting greater trust in leadership, satisfaction (...) with supervision, leader–member exchange quality, affective organizational commitment, and forgiveness than those reporting insincere or no apologies. A mediation model was supported, showing that attributions of apology sincerity fostered perceptions of humility, which enhanced perceptions of transformational leadership, and consequently garnered more positive follower reactions. (shrink)

In their paper “Brain Data in Context: Are New Rights the Way to Mental and Brain Privacy?” Susser and Cabrera (2024) argue against the notion that specific rights may be necessary to protect “brai...

The issue of trust has increasingly attracted attention in the business ethics literature. Our aim is to contribute further to this literature by examining how the use of the carbon copy function in email communication influences felt trust. We develop the argument that the use of cc enhances transparency—representing an important characteristic of workplace ethics—and hence promotes trust. We further argue that a downside of the cc option may be that it can also be experienced as a control mechanism, which (...) may therefore negatively affect trust. The results of our first study showed that the use of cc indeed enhances perceived transparency, but at the same time also leads to the experience of increased control. Building upon this insight, the findings of five subsequent studies consistently revealed that the use of cc negatively influences felt trust. More precisely, employees felt trusted the least when the supervisor was always included in cc. This effect on felt trust also negatively influenced how trustworthy the organizational climate was perceived. We further replicated these results in two field surveys, which showed that the negative effect of cc on felt trust lowered perceptions of psychological safety and contributed to a culture of fear. Taken together, our findings suggest that when transparency in email communications is experienced as a control mechanism, its use is perceived as unethical, rather than as ethical. Implications and recommendations for future business ethics research are discussed. (shrink)

In this essay, I argue that exploring institutional racism also needs to examine interactions and communications between patients and providers. Exchange between bioethicists, social scientists, and life scientists should emphasize the biological effects—made evident through health disparities—of racism. I discuss this through examples of patient–provider communication in fertility clinics in South Africa and the ongoing COVID-19 pandemic to emphasize the issue of mistrust between patients and medical institutions. Health disparities and medical mistrust are interrelated problems of racism in healthcare provision.

In the wake of recent corporate scandals, this paper traces the growing power of pension funds to provide managerial oversight of the firms they hold in their investment portfolios. Increasingly pension funds are exercising their legitimate rights as owners to raise the corporate governance standards of the firms they invest in. Within corporate governance generally, pension funds are shifting their attention away from managerial accountability and toward measures that increase transparency in firm-level decision-making. Pension funds use transparency to ensure that (...) shareholders are the primary interest being served by the firm. Transparency not only aligns managers and owners, it also raises issues of firm behaviour that allow other stakeholders to engage the corporation more broadly. I contend that secrecy is economically inefficient. When organizations are opaque and interests are secret, decision-making can and does distort efficiency. I examine recent pension fund corporate governance campaigns with particular reference to the California Public Employees Retirement System. (shrink)

Annotation Up-to-date and accessible examination of scientific thinking about the nature of consciousness. Chris Nunn sets out the most exciting theoretical and experimental advances in this fast developing and controversial area.

Philosophical descriptions of democratic music education frequently rely on “inclusion” and “participation” as the defining features of democratically oriented music programs. Democratic epistemic considerations, such as regulatory ideals of musical quality and excellence, however, are less commonly cited, if not actively avoided. This paper addresses several primary reasons for the paucity of epistemic considerations in democratic music education and problematizes current concerns about epistemic judgements from a democratic perspective. Drawing on Miranda Fricker’s influential concept of epistemic injustice, this paper argues (...) that democratic dialogue that respects values of diversity and inclusion cannot legitimately ignore epistemic dimensions because doing so occludes the epistemic dimensions of cultural, racial, and gender diversity in music education classrooms. (shrink)

In “Ethical Responsibilities for Companies that Process Personal Data” McCoy et al. (2023) proposed three substantive principles that should underlie corporations’ treatment of data: minimizing har...

Donald Davidson argues that ‘the stabbing of Caesar’ and ‘the killing of Caesar’ are two descriptions of the one event whereas Jaegwon Kim contends events are more fine-grained and two events occurred, related by supervenience. I argue that neither solution is satisfactory and, inspired by Lynne Rudder Baker, I develop a constitution relation governing cooccurring, co-located events such that the stabbing of Caesar comes to constitute the killing of Caesar when the stabbing occurs in the appropriate circumstances. According to my (...) view, the stabbing of Caesar is metaphysically distinct from the killing of Caesar such that the killing is dependent on the stabbing, yet is not identical to it. (shrink)

In a recent article (Inquiry, Vol. 19 [1976]), J. W. Meiland addresses the issue of psychologism in logic, which holds that logic is a branch of psychology and that logical laws (such as the Principle of Non?Contradiction) are contingent upon the nature of the mind. Meiland examines Husserl's critique of psychologism, argues that Husserl is not convincing, and offers two new objections to the psychologistic thesis. In this paper I attempt to rebut those objections. In question are the acceptable criteria (...) for determining the possibility or impossibility of systems of logic significantly different from our own. I argue that a criteriological application of our accepted laws of logic to this question commits a circular fallacy. I then argue that, even if we accept logical consistency as a criterion for possibility, a plausible argument for the possibility of valid alternative logics can be constructed by using the functionalist analogy between minds and automata. Finally, I attempt to rebut the claim that in logic the only changes possible are conceptual changes that would not permit a proposition to be both true and false. (shrink)

Easy-to-follow step-by-step instructions take little ones through a grounding series of basic yoga poses. Simple, descriptive language invites young children to pretend to be a bear, moving their furry bodies into specific yoga poses designed to both energize and inspire bravery.

From the seventeenth century onwards, English Reformed ministers engaged in lively correspondence and publishing exchanges with men from different countries and Protestant traditions. In the eighteenth century, appreciation of their shared intellectual and cultural heritage and a desire to sustain the patterns for religious living it encouraged inflected the content and style of textual interactions among Halle Pietists, English dissenters and New England Congregationalists. Interest in the present state of religious life was also important, and therefore news about awakenings and (...) materials for pastoral care circulated around Europe and North America through existing channels and by new means. Their encounters and the texts that they produced were mutually generative, and the language and manner of the participants' personal interactions were important features of published works. These personal associations, publishing activities and discursive styles can be understood as aspects of the literary sociology of a religious culture that valued intellectual and emotional engagements and sought to inculcate religion through education and friendship. (shrink)

In language, recombination of a discrete set of meaningless building blocks forms an unlimited set of possible utterances. How such combinatorial structure emerged in the evolution of human language is increasingly being studied. It has been shown that it can emerge when languages culturally evolve and adapt to human cognitive biases. How the emergence of combinatorial structure interacts with the existence of holistic iconic form-meaning mappings in a language is still unknown. The experiment presented in this paper studies the role (...) of iconicity and human cognitive learning biases in the emergence of combinatorial structure in artificial whistled languages. Participants learned and reproduced whistled words for novel objects with the use of a slide whistle. Their reproductions were used as input for the next participant, to create transmission chains and simulate cultural transmission. Two conditions were studied: one in which the persistence of iconic form-meaning mappings was possible and one in which this was experimentally made impossible. In both conditions, cultural transmission caused the whistled languages to become more learnable and more structured, but this process was slightly delayed in the first condition. Our findings help to gain insight into when and how words may lose their iconic origins when they become part of an organized linguistic system. (shrink)

Nobel Prize winner Richard Thaler was among those who expected Remain to win the EU referendum. Yet on 23 June 2016, a majority in the UK voted to Leave by a margin of 52–48%. A study of over 450 Leave voters, based on the MINDSPACE framework, looks at whether behavioural factors affected the outcome and at what lessons could be learned for any future votes. It finds that voters had low levels of knowledge which may have undermined any ‘status quo (...) bias’; that messengers used by the Remain campaign didn’t work for this audience; that the Remain campaign’s loss-framed figure of £4300 per household per year was judged to be less than the Leave campaign’s figure of £350 m a week (it is six times larger); and that behaviourally-based arguments on immigration might have had an impact. It notes how behavioural science was used successfully to increase turnout. The implication for communicators is that a ‘Test, Learn, Adapt’ strategy could be helpful in future campaigns. (shrink)

This paper claims rigour and sensitivity for a methodology used to explore multiple sources of data and expose the essential characteristics of a phenomenon in the human sciences. A descriptive phenomenological methodology was applied in a study of the experience of ten people with osteoarthritis receiving ginger compress therapy. The application of the phenomenological attitude, with reduction, bracketing and imaginative variation, allowed multiple sources of data – written, pictorial and oral – to be explicated. The applied methodology used is described (...) in this paper, with its six clearly defined steps illustrated by examples from the study. The findings demonstrate that phenomenological reduction enabled an indication of the potential benefits of ginger compress treatment as a therapy for people with osteoarthritis. Indo-Pacific Journal of Phenomenology , May 2010, Volume 10, Edition 1. (shrink)

There has been considerable public debate on a range of complementary health practices throughout the western world, perhaps especially in Australia, United States and Europe. Most often, the research critique of these practices is restricted to quantitative or non-user qualitative research methodologies. Consequently, there is a significant gap in the research profile of complementary health services that needs to be addressed particularly in view of the rapid and ongoing increase in the use of complementary services, even in the face of (...) sometimes adverse media publicity. This paper demonstrates the contribution that phenomenologically based research can make to fill this lacuna by explicating, in detail, the client experience of a complementary health practice. The paper explores patient experience of a ginger compress, as applied by anthroposophically trained nurses, to demonstrate various therapeutic effects. Four key themes emerged including an increase in warmth and internal activity in the major organs of the body, changes in thought-life and sensory perception along with a greater sense of well-being and self-focus with the perception of clearer personal boundaries. These themes, emerging from a patient sample in New Zealand, compared favourably to the Filderklinik Study completed in 1992 in a large German state hospital. Indo-Pacific Journal of Phenomenology , Volume 4, Edition 1 July 2004. (shrink)

Warren and Dresang comment on the contributions from a psycholinguistic perspective, highlighting close relations between the respective research on events and proposing that, for example, verbs may indeed directly pre‐activate templates of the typically involved event participants.

Environmental education aims to affect environmental knowledge and attitude to ultimately induce pro-environmental behavior. Based on 247 upper elementary school students, we tested the impact of an outdoor-based earth education program on environmental knowledge and attitude with a pre-post design. Both outcome measures were Rasch scales. Environmental knowledge is a composite of 27 system, action, and effectiveness knowledge items, and environmental attitude is a composite of 13 evaluative statements and 11 self-reported behaviors about nature preservation. Our analysis revealed gains in (...) environmental knowledge and attitude. The convergence between knowledge and attitude increased significantly from pre- to post-program, and attitude played a significant role in knowledge acquisition. (shrink)

The compelling case that Anderson makes for neural reuse and against modularity as organizing principle of the brain is further supported by evidence from developmental disorders. However, to provide a full evolutionary-developmental theory of neural reuse that encompasses both typical and atypical development, Anderson's (MRH) could be further constrained by considering brain development across ontogeny.

Before any attempt is made to solve the problem with which this paper deals, it is necessary to convince the reader that the problem exists. Much is written and said to-day about class distinctions, both by those who announce with satisfaction their growing disappearance, and by those who half guiltily admit their existence, but it never seems to occur to such writers that the nature of these distinctions is itself something of a mystery. We take it for granted as one (...) of the most obvious and commonplace facts of daily life. It seems hardly likely that the examination of a thing so ubiquitous and immemorial will yield anything new. My object will be to maintain that this attitude is mistaken, and that the idea of “class” is not really self-explanatory, but deserves a closer analysis than it usually gets. And if this proves to be the case, it must be admitted that the subject is of importance. Many political and social problems are deeply involved in the fact of class distinctions. Many who believe in a possible regeneration of human society would gladly surrender much to secure a world where poverty should be no more, yet hesitate before the prospect of a loss, through diffusion, of cultural values which they feel to be infinitely precious, and which give to the existing order a greater claim to permanence than it would otherwise possess. We most of us hardly know our own minds in this matter. We yield social distinctions their place, but we do so shamefacedly, as though confessing to a mere unjustified conservatism. (shrink)

Contemporary theories of consciousness are based on widely different concepts of its nature, most or all of which probably embody aspects of the truth about it. Starting with a concept of consciousness indicated by the phrase “the feeling of what happens” (the title of a book by Antonio Damásio), we attempt to build a framework capable of supporting and resolving divergent views. We picture consciousness in terms of Reality experiencing itself from the perspective of cognitive agents. Each conscious experience is (...) regarded as composed of momentary feeling events that are combined by recognition and evaluation into extended conscious episodes that bind cognitive contents with a wide range of apparent durations (0.1 secs to 2 or more secs, for us humans, depending on circumstances and context). Three necessary conditions for the existence of consciousness are identified: a) a ground of Reality, envisaged as an universal field of potentiality encompassing all possible manifestations, whether material or 'mental'; b) a transitional zone, leading to; c) a manifest world with its fundamental divisions into material, 'informational' and quale-endowed aspects. We explore ideas about the nature of these necessary conditions, how they may relate to one another and whether our suggestions have empirical implications. (shrink)

De Bie et al. (2023) found that most feminist literature praises Artificial Womb Technologies (AWT) for its potential to increase equality among the sexes. This literature frames gestation as a poi...

This study examines the influence of a dimension of a strategic organizational change context—namely informational distance—on employees’ justice expectations and their behavioral intentions toward the change. Drawing on research from organizational justice and from construal level theory, we hypothesize that informational distance, i.e., the extent to which employees feel knowledgeable about the coming change, affects the relative influence of the anticipatory justice facets and anticipatory overall justice in predicting support for change. Consistent with the hypotheses, results from participants of a (...) merger suggest that when employees feel less knowledgeable about the future change, overall anticipatory justice predicts their intention to cooperate with the change. However, when employees feel more knowledgeable about the future change, anticipatory justice facets predict intention to cooperate. Implications for research on organizational justice and change as well as considerations for practice are discussed. (shrink)

I begin by evaluating four theories: mereological essentialism, the occasional identity thesis, four-dimensionalism and the constitution view. I compare the solutions these theories offer to puzzles of material constitution with particular attention being paid to their treatment of Leibniz’s Law, the ontological status of objects and the distinction between objects and their matter. If a lump of clay constitutes a statue, the lump of clay and the statue are metaphysically distinct such that they are distinct kinds, but numerically one thing—the (...) statue as constituted by the lump of clay. I defend this view against criticism that it collapses into identity or substance dualism, exploding reality with unnecessary objects. I amend constitution to better account for cases of composite objects and to better solve puzzle cases involving change in parts over time. Finally, I go on to apply constitution to an unorthodox puzzle for theories of objects—the problem of the individuation of events. Events are things that happen. If we grant that events are in the same or similar ontological category to objects, there is a strong analogy between the problem of material constitution and the problem of events. In signing the US Constitution you may also do your bit to ratify it. However, the signing and the ratifying have different properties. I suggest that the signing and the ratifying are distinct in kind, but are not two separate events. I develop a constitution relation—a contingent, irreflexive, asymmetric and transitive relation—for events. This relation has the potential to be applied to the mind-body problem. (shrink)

Part of the normalization of assisted reproductive technologies is the premise that the children born from in vitro fertilization are no different from their counterparts conceived spontaneously. However, interest in peri-conception health and new epigenetic understandings of biological plasticity has led to some questioning the presumed irrelevance of conception in vitro, and when doing so, describing IVF children as “apparently healthy.” Taking “apparently” and “healthy” seriously, this article explores how modes of attention—ways of naming and framing embryo potentiality—shape understandings of (...) health and normality. I contend that understanding the politics of potentiality, and how they may emerge in a postgenomic age, requires an unpacking of various modes of attention and framing. Ethnographic findings from South Africa’s fertility clinics and emerging literature on epigenetic variation in IVF conception demonstrate how, under a genetic mode of attention, IVF clinics views “abnormality” as fated, unviable, and discardable. Exploring the possibility of answering the postgenomic questions to IVF reveals structural challenges to knowing long-term health implications. Incipient attempts within the fertility clinic at managing these questions shows various strategic techniques, such as leveraging epigenetics to marketable ends and shifts to individual responsibility. (shrink)

Following her abdication, Queen Christina of Sweden took up residence in the Palazzo Farnese, Rome from 1655. She had already developed a keen interest in music, gained from tuition from a French dancing master, and playing the star role in the ballet The Captured Cupid in honour of her mother's birthday in 1649. Christina's arrival in Rome was marked by performances in her honour in the Palazzo Barberini and Palazzo Pamphili of specially commissioned works by contemporary composers Marco Marazzoli and (...) A.F. Tenaglia, and by her favourite Giacomo Carissimi. Inspired by the chamber music proportions of the cappella of the Collegio Germanico, many of Carissimi's secular arias were composed for his royal Swedish patron. After two years in France, Christina returned to Rome, where she took up residence in the Palazzo Riario on the Janiculum. Inventories record her musical instruments and describe the contents of the Great Hall in which concerts were held. (shrink)